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ANSWERS & MARK SCHEMES. MEIOSIS AND VARIATION. A2.8. QUESTIONSHEET 1. FEATURE. MITOSIS. MEIOSIS. Involves two successive nuclear divisions.
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Involves two successive nuclear divisions 7 3 Does not occur in a haploid cell 7 3 Involves synapsis forming bivalents 7 3 Involves chiasmata formation 7 3 Leads to random assortment of chromatids 7 3 Leads to random assortment of chromosomes 7 3 Occurs during gamete formation in a mammal 3 3 Daughter nuclei have identical genetic content 3 7 DNA replicates before cell division commences 3 3 Involves two chromosomal replications 7 7
TOTAL 9
(a) B A C; A= anaphase, B = prophase, C = telophase; 2
(b) Structure: chromosomes would be replicated into chromatids; chiasmata would be showing between chromatids of homologous chromosomes;
Arrangement: chromosomes would be arranged into homologous pairs; with centromeres attached to the opposite spindles; 4
(c) (i) 2; (ii) 4; (iii) 6; 3
TOTAL 9
(a) in animals consists of a furrowing/tucking in of the cell membrane; eventually separating two nuclei by constriction (of cytoplasm); in plants a cell plate/ middle lamella is synthesised between nuclei; calcium /magnesium pectate/cellulose secreted to form new cell wall; 4
(b) centromere in chromosome holds chromatids together; provides attachment to spindle during cell division; centriole is made of microtubules (in animal cells); forms spindle during cell division; 4
(c) synapsis is pairing of homologous chromosomes; in zygotene/early prophase of meiosis; chiasmata formation occurs in diakinesis/late prophase of meiosis; is cross over of genetic material between chromatids of homologous chromosomes; 4
TOTAL 12
(a) DNA double helix unwinds to give single stranded (primer) DNA; upon which the complementary strand is assembled; from surrounding nucleotides; forming double stranded daughter DNA; thus each new DNA has one strand from parent DNA and one new strand; max 4
(b) genes consist of alleles at corresponding loci on homologous chromosomes; all alleles on a particular chromosome/chromatid must be carried together during inheritance; chiasmata will swap some of these alleles with those on the sister chromosome; thus the allelic make up of the linkage groups is modified; 4
(c) meiosis reduces two sets of chromosomes to one set/diploid state to haploid state; fertilisation joins two haploid nuclei together restoring the diploid state; 2
TOTAL 10
(a) A = chromatid; B = spindle fibre; C = centriole; D = centromere; E = chiasma; 5
(b) (i) mitosis; (ii) metaphase; (iii) meiosis; (iv) early anaphase I; 4
(c) cell 2; it is purely random which chromosomes of the homologous pairs go to a particular pole; thus groups of alleles/linkage groups are mixed up in random fashion; giving continuous variation; 3
(d) will mix up alleles between linkage groups into new combinations; giving (more) variation; 2
TOTAL 14
(a) 6 chromosomes in a row on equator; same morphology of chromosomes as in metaphase 1 of meiosis diagram; quality and clarity of diagram; (chromosomes can be in any order but must not be paired or show chiasmata) 3
(b)
Any two of the labels (reject chiasmata) - 2 marks;; chromosomes correctly segregating to poles (in correct order and shape); spindle and completed chiasmata correctly shown; quality and clarity of diagram; (clean, well drawn, joined up lines/ no shading /reasonable size) 5
TOTAL 8
centromere
aster
spindle fibre
chromatids
(a) mitosis maintains the same chromosome number (reject diploid state since mitosis can take place as haploid to haploid) whereas meiosis halves the chromosome number/reduces the diploid state to the haploid state; mitosis maintains the same genotype whereas meiosis introduces genetic variation; 2
(b) random assortment of chromosomes at Anaphase 1; random assortment of chromatids at Anaphase 2 ; formation of chiasmata; 3
(c) best answered by a genetic diagram, eg.
gametes A a A a equal proportions of each gamete; Fl AA Aa Aa aa A is dominant so 3 dominants to 1 recessive; 3
TOTAL 8
Feature Mitosis Meiosis 1 Meiosis 2 Occurs during gametogenesis √ √ √ ; DNA replicates before prophase √ √ × ; Bivalents form during prophase × √ × ; Chiasmata are formed × √ × ; Chromatids randomly assort during anaphase × × √ ; TOTAL 5
(1 mark per correct line)
do not accept √