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Familial Polyposis Coli, Study Guides, Projects, Research of Medical Sciences

King George's Medical UniversityMedical Sciences

Information on Familial Polyposis Coli, a rare autosomal dominant disease that affects males more than females. The document covers the incidence, aetiology, pathology, complications, clinical picture, and investigations of the disease. Familial Polyposis Coli is characterized by the presence of multiple polyps in the colon and rectum, which can lead to malignancy in 100% of cases by the age of 40-50 years. The document also mentions Gardner's syndrome, a type of familial polyposis coli with additional symptoms.

Typology: Study Guides, Projects, Research

2022/2023

Available from 02/11/2023

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Download Familial Polyposis Coli and more Study Guides, Projects, Research Medical Sciences in PDF only on Docsity!

Familial Polyposis Coli * Incidence :It is a rare disease affecting males more than females . * Aetiology : = It is autosomal dominant disease . = 50% of the children of an affected parent have this disorder . = Only individuals with polyps transmit the disease. * Pathology : = The colon and rectum are full of multiple ( at least 100), sessile and pedunculated polyps . = Rectum and sigmoid colon are the commonest site of affection . = There 3 histological types (tubular ,villous and tubulovillous). = Gardner’s syndrome : is a type of familial polyposis coli with polyps in GIT,osteomas of mandible & skull and desmoid tumors of the abdominal wall . SESBILE POLYPS Hyperpiastic polyp Adenoma TERT pose ubenucoas, Huseutsris propria AGENOMAS, Pocunculated Sessite Tubular Vallous: