Colloids and their role in
Pharmaceutical
Industry
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Colloids and it's properties ,colloidal dispersion, Assignments of Pharmacy
Classification of dispersed systems & their general characteristics, size & shapes of colloidal particles, classification of colloids & comparative account of their general properties. Optical, kinetic & electrical properties. Effect of electrolytes, coacervation, peptization& protective action
Typology: Assignments
2020/2021
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Colloids and their role in
Pharmaceutical
Industry
Colloids
A mixture in which very small particles of one substance are
distributed evenly throughout another substance.
Introduction
The word “colloid” was derived from the Greek, “kolla” for
glue.
Colloid is short synonym for colloidal system.
The heterogeneous biphasic system.
Size of colloidal particle ranges from 1nm to 100nm.
Classification
There two criteria's for classification of
are
colloids.
**1. Based on the state of Aggregation of phase
- Based on the interaction of phase**
Interaction of phase
On the basis of affinity between two
phases, colloidal solutions are classified into
- Lyophobic
sols Examples
sols of Metals,
sulphur
2. Lyophilic sols
Examples gums,
Preparation
used for
the
Two methods are generally
preparation of colloidal
solutions.
**1. By Condensation
- By Dispersion**
Kinetic properties
Brownian motion
Rapid, random, zigzag movement of colloidal
particles through dispersion medium.
This movement is due to bombardment of
colloidal particles by the molecules of
dispersion medium.
Optical properties
Tyndall Effect
Light scattering by colloidal particles.
Bright cone of scattered light is called Tyndall
cone.
Purification
The colloidal solutions prepared by any
method contain different impurities.
They can be separated by
**1. Dialysis
- Ultrafiltration**
Role in pharmaceutics
Therapy
Colloidal system are used as therapeutic
agents in different areas.
Colloidal medicines are more effective and are
easily absorbed in our system.
Example ,penicillin and streptomycin.
Colloidal sulphur
It is used as disinfectants.
It is a homeopathic
remedy used to treat
skin conditions such as
psoriasis, eczema etc.
Colloidal copper
It is used in treatment of
cancer.
It is used as a remedy for
burns, arthritis, parasites,
viral and bacterial infections.
Colloidal silver
It is an unrivalled anti-biotic.
It destroy all types of virus, bad fungi and
bacteria.
It promotes healing.
Colloidal electrolytes
Increase solubility, stability and taste of
compounds
Used as additives in drugs
E.g. Quaternary Ammonium salts