BIOSTATISTICS LECTURE NOTES, Lecture notes of Biostatistics

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Subclinical Figure 1.18 Natural History of Disease Timeline Usval Teme ™ Clinical Pathologie Onaet of Expowwe Changes Symotoms . ‘ oe ot a ee Outcome PERIOD OF PRE-PATHOGENESIS PERIOD OF PATHOGENESIS DISEASE PROCESS | —> Before man DEATH [Cheonte state The course of the disente In man —> LEVELS OF PRIMARY PREVENTION SECONDARY PREVENTION PREVENTION TERTIARY PREVENTION MODES OF | HEALTH *_-sreciric [eamay biaGnosis | pisapinY SS! INTERVENTION PROMOTION PROTECTION| AND TREATMENT | LIMITATION | REHABILITATION Susceptibility Levels of Prevention y EXPOSURE ¢ Before risk factors Adaptation * Pre-pathogenesis ¢ Subclinical or very early clinical ~] ¢ Middle to late clinical eS Oe se Level of Prevention Primordial Preyention Asymptomatic pase Clinical course Primary Prevention Secondary Prevention Tertiary Prevention Epidemiologic Triad