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Basic Medical Microbiology Questions, Quizzes of Medical Microbiology

This is a multiple-choice type of questions from the following topics: - Microbial Taxonomy - Bacterial Genetics, Metabolism, and Structure - Host-Microorganism interactions The answers and rationale can be find in the last page of the document

Typology: Quizzes

2016/2017

Available from 12/05/2024

agtstudies
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1. Which taxonomic tool analyzes microbial fatty acid profiles for classification?
A) Polyphasic taxonomy
B) MALDI-TOF MS
C) Chemotaxonomic methods
D) Nucleic acid hybridization
2. The threshold for genome-to-genome distance (GGD) to confirm species-level similarity is:
A) 80%
B) 60%
C) 70%
D) 90%
3. Which phenotypic trait is least reliable for bacterial classification?
A) Staining characteristics
B) Colony morphology
C) Nutritional requirements
D) Antibiotic resistance
4. What is the key difference between the Archaea and Bacteria domains?
A) Presence of peptidoglycan
B) DNA composition
C) Cell membrane lipid composition
D) Ribosome structure
5. In binomial nomenclature, which is correctly formatted?
A) Staphylococcus aureus
B) staphylococcus aureus
C) Staphylococcus Aureus
D) Staphylococcus aureus
6. Which genetic process involves the uptake of naked DNA by bacteria?
A) Transduction
B) Conjugation
C) Transformation
D) Mutation
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  1. Which taxonomic tool analyzes microbial fatty acid profiles for classification?
    • A) Polyphasic taxonomy
    • B) MALDI-TOF MS
    • C) Chemotaxonomic methods
    • D) Nucleic acid hybridization
  2. The threshold for genome-to-genome distance (GGD) to confirm species-level similarity is:
    • A) 80%
    • B) 60%
    • C) 70%
    • D) 90%
  3. Which phenotypic trait is least reliable for bacterial classification?
    • A) Staining characteristics
    • B) Colony morphology
    • C) Nutritional requirements
    • D) Antibiotic resistance
  4. What is the key difference between the Archaea and Bacteria domains?
    • A) Presence of peptidoglycan
    • B) DNA composition
    • C) Cell membrane lipid composition
    • D) Ribosome structure
  5. In binomial nomenclature, which is correctly formatted?
    • A) Staphylococcus aureus
    • B) staphylococcus aureus
    • C) Staphylococcus Aureus
    • D) Staphylococcus aureus
  6. Which genetic process involves the uptake of naked DNA by bacteria?
    • A) Transduction
    • B) Conjugation
    • C) Transformation
    • D) Mutation
  1. What enzyme is central to DNA replication in bacteria?
    • A) RNA polymerase
    • B) DNA polymerase
    • C) Helicase
    • D) Topoisomerase
  2. Which process results in antibiotic resistance via gene cassette acquisition?
    • A) Plasmid transfer
    • B) Transduction
    • C) Transposon-mediated insertion
    • D) Horizontal gene transfer
  3. A mutation that results in a stop codon is called:
    • A) Silent mutation
    • B) Missense mutation
    • C) Frameshift mutation
    • D) Nonsense mutation
  4. What is the role of RecA in bacterial recombination?
    • A) Facilitating DNA repair and homologous recombination
    • B) Synthesizing DNA
    • C) Breaking hydrogen bonds in double-stranded DNA
    • D) Inhibiting transcription factors
  5. Which molecule acts as the final electron acceptor in aerobic respiration?
    • A) Nitrogen
    • B) Oxygen
    • C) Sulfate
    • D) Carbon dioxide
  6. What pathway produces both NADPH and ribose- 5 - phosphate?
    • A) Glycolysis
    • B) TCA cycle
    • C) Pentose phosphate pathway
    • D) Fermentation
  1. Which bacterial toxin inhibits protein synthesis by targeting EF-2?
    • A) Shiga toxin
    • B) Diphtheria toxin
    • C) Cholera toxin
    • D) Botulinum toxin
  2. What is the first step in establishing infection by a pathogen?
    • A) Invasion
    • B) Dissemination
    • C) Colonization
    • D) Adhesion
  3. Which component of the Gram-negative bacterial wall acts as an endotoxin?
    • A) Lipoteichoic acid
    • B) Peptidoglycan
    • C) Lipopolysaccharide (LPS)
    • D) Capsule