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Anatomy and Physiology of Digestive system, Lecture notes of Anatomy

Digestive Sytem Anatomy and Physiology Nursing Prof. Jennie Corpus

Typology: Lecture notes

2023/2024

Available from 09/27/2024

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DIGESTIVE SYSTEM ANATOMY & PHYSIOLOGY
Functions of the Digestive System
Ingestion:
Active, voluntary process
Food must be placed into the mouth before it can be acted on
Propulsion:
If foods are to be processed by more than 1 digestive organ they
must be propelled from one organ to the next
Peristalsis involuntary, alternating waves of contraction and
relaxation of the muscles in the organ wall
Food
breakdown:
Mechanical digestion prepares food for further degradation by
enzymes
Examples:
o Mixing of food in the mouth by the tongue
o Churning of food in the stomach
o Segmentation in the small intestine
Food
breakdown:
Chemical digestion sequence of steps in which large food
molecules are broken down into their building blocks by enzymes
Absorption:
Transport of digested end products from the lumen of the GI tract
to the blood or lymph
Digested foods must 1st enter the mucosal cells by active or passive
transport process (for absorption to happen)
Defacation:
Elimination of indigestible residues from the GI tract via the anus
(form of feces)
Anatomy of the Digestive System
o Organs of the digestive system can be separated into 2 main groups:
Alimentary canal, and
Accessory digestive organs
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 DIGESTIVE SYSTEM ANATOMY & PHYSIOLOGY

Functions of the Digestive SystemIngestion:Active , voluntary process  Food must be placed into the mouth before it can be acted on  Propulsion: ^ If foods are to be processed by^ more than 1^ digestive organ^ they must be propelled from one organ to the nextPeristalsisinvoluntary , alternating waves of contraction and relaxation of the muscles in the organ wall  Food breakdown:Mechanical digestion – prepares food for further degradation by enzymes  Examples : o Mixing of food in the mouth by the tongue o Churning of food in the stomach o Segmentation in the small intestine  Food breakdown:Chemical digestionsequence of steps in which large food molecules are broken down into their building blocks by enzymes  Absorption:  Transport of digested end products from the lumen of the GI tract to the blood or lymph  Digested foods must 1st^ enter the mucosal cells by active or passive transport process (for absorption to happen )  Defacation:  Elimination of indigestible residues from the GI tract via the anus (form of feces )  Anatomy of the Digestive System o Organs of the digestive system can be separated into 2 main groups :  Alimentary canal , and  Accessory digestive organs

Organs of the Alimentary Canal o Also called the gastrointestinal tract o Continuous, hollow muscular tube that winds through the ventral body cavity o Open at both ends  Mouth o Food enters the digestive tract through the mouth or oral cavity  A mucous membrane-lined cavityLips:  ( Labia )  Protects its anterior opening  Cheeks: ^ Form its lateral walls  Palate:  Divides into 2 : o Hard palate – forms its anterior roof o Soft palate – forms its posterior roofUvula:Fleshy finger-like projection of the soft palate  Extends inferiorly from the posterior edge of the soft palate  Vestibule:Space between the lips and the cheeks externallySpace between teeth and gums internallyOral cavity proper:  Area contained by the teethTongue:  Muscular tongue  Occupies the floor of the mouth  Has several bony attachments , 2 of these are: o Hyoid bone , and o Styloid processes of the skullLingual frenulum:  Fold mucous membrane  Secures the tongue to the floor of the mouth  Limits its posterior movements  Palatine tonsils:  Paired masses of lymphatic tissue  Found at the posterior end of the oral cavity  Lingual tonsil:  Cover the base of the tongue just beyond  Pharynx o From the mouth , food passes posteriorly into the:  Oropharynx:Posterior to the oral cavity  Laryngopharynx: ^ Continuous with the^ esophagus^ below  Common passageways for food , fluids , and airEsophagus o Also called gullet o Runs from the pharynx through the diaphragm to the stomachSize & function:25 cm ( 10 inches ) long  Passageway that conducts food by peristalsis to the stomach  Structure:  Made up of the same four basic tissue layers or tunicsMucosa:Innermost layer  Moist membrane that lines the cavity or lumen  Consist primarily of surface epithelium  Plus a small amount of connective tissue ( lamina propria ) o A scanty smooth muscle layerSubmucosa: ^ Found just beneath the mucosa  Soft connective tissue layer containing blood vessels , nerve endings , lymph nodes , and lymphatic vesselsMuscularis externa:  A muscle layer typically made up of an inner circular layer  Outer longitudinal layer of smooth muscle cells

Lesser curvature:Concave medial surface  Lesser omentum:  Double layer of peritoneum  Extends from the liver to the greater curvature  Greater omentum: ^ Another extension of the peritoneum  Drapes downward and covers the abdominal organs  Stomach mucosa:  Simple columnar epithelium composed entirely of mucous cells  Produce a protective layer of bicarbonate-rich alkaline mucus  Clings to the stomach mucosa  Protects the stomach wall from being damaged by acid and digested by enzymes  Gastric glands:  Smooth lining dotted with millions of deep gastric pits  Secrete the solution called “ gastric juice ”  Intrinsic factor:  Substance needed for the absorption of vitamin B12 from the small intestine  Chief cells:  Produce protein-digesting enzymes  Mostly pepsinogensParietal cells: ^ Produce corrosive^ hydrochloric acid o Makes the stomach contents acidic and activates the enzymesEnteriendocrine cells:  Produce local hormones such as gastrin o Important to the digestive activities of the stomach  Chyme:Heavy cream that resembles after the food has been processed  Small Intestine o Body’s major digestive organ  Location:Muscular tube extending from the pyloric sphincter to the large intestine  Size:Longest section of the alimentary tube  Average length of 2.5 to 7 m ( 8 to 20 feet ) in a living person

Subdivisions:3 subdivisions : o Duodenum – contribute 5% o Jejunum – contribute 40% o Ileum – contribute 60%Ileocecal valve:Joins the large and small intestineHepatopancreatic ampulla:Flask-like  Literally the “ liver-pancreatic-enlargement ”  Microvilli: ^ Tiny projections of the plasma membrane  Give cell surface a fuzzy appearance “ brush border ” o Complete the digestion of proteins and carbohydratesVilli:Finger-like projections of the mucosa  Give it a velvety appearance and feel o ( like the soft nap of a towel )  Lacteal:  Rich capillary bed and a modified lymphatic capillary  Circular folds:  Also called “ Plicae circulares ”  Deep folds of both mucosa and Submucosa layer  Do not disappear when food fills the small intestine  Peyer’s patches:  Resemble the look of the tonsilsCapture and destroy bacteria  Large Intestine o Much larger in diameter than the small intestine o But shorter in lengthSize: ^ 1.5 m^ ( 5 feet )^ longExtends from the Ileocecal valve to the anusFunctions:Dry out indigestible food residue by absorbing water  Eliminate residues from the body as feces  Subdivisions: ^ Frames the small intestines on^ 3 sidesSubdivisions : Cecum , Appendix , Colon , Rectum , and Anal canalCecum:Saclike cecum1 st^ part of the large intestine  Appendix:Wormlike appendix  Potential trouble spot  Ideal location for bacteria to accumulate and multiply  Ascending colon:  Travels up the right side of the abdominal cavity  Makes a turn, the right colic (or hepatic ) flexure ,

Crown:Enamel - covered crown  Exposed art of the tooth above the gingival or gumEnamel:Hardest substance in the body  Fairly brittle (heavily mineralized with calcium salts )  Root:  Outer surface of the root is covered by a substance ( cementum ) o Attaches the tooth to the periodontal membrane ( ligament )  Dentin:Bonelike material  Underlies the enamel and forms the bulk of the tooth  Pulp cavity:  Surrounds a central pulp cavity  Contains a number of structures ( connective tissue , blood vessels , and nerve fibers ) collectively called the pulpRoot canal:  Pulp cavity extends into the root  Becomes the root canal  Provides a route for blood vessels , nerves and other pulp structuresSalivary Glands o 3 pairs of salivary glands o Empty their secretions into the mouth  Parotid glands:  Lie anterior to the ears  Empty their secretions into the mouth  Submandibular and sublingual glands:  Empty their secretion into the floor of the mouth through tiny ducts  Saliva:Product of salivary glands  Mixture of mucus and serous fluidsSalivary amylase:Clear serous portion contains an enzymeBicarbonate-rich juice  Begins the process of starch digestion in the mouth  Pancreas o Produces enzymes o Break down all categories of digestible foods  Location:  Pancreas is a soft , pink triangular gland  Extends across the abdomen from the spleen to the duodenum  Lies posterior to the parietal peritoneum  Location referred to as retroperitonealPancreatic enzymes:  Secreted into the duodenum in an alkaline fluidNeutralizes the acidic chyme coming in from the stomach  Endocrine function:  Produces hormones insulin and glucagon

Liver o Largest gland in the body  Location:  Located under the diaphragm (more to the right side of the body)  Overlies and almost completely covers the stomach  Falciform ligament:  Delicate mesentery cord  Liver has 4 lobes  Suspended from the diaphragm and abdominal wall  Function: ^ Liver’s digestive function is to produce^ bileBile:Yellow-to-greenWatery solution containing bile salts , bile pigments , cholesterol , phospholipids , and a variety of electrolytesBile salts:  Emulsify fats by physically breaking large fat globules into smaller ones  Providing more surface area for the fat - digesting enzymes to work on  Gallbladder o Bile is concentrated by the removal of waterLocation:Small , thin-walled green sacSnuggles in a shallow fossa in the inferior surface of the liver  Cystic duct:  Bile backs up the cystic duct  Enters the gallbladder to be stored  Physiology of the Digestive System o Digestive system takes in food ( ingest it ), breaks it down physically and chemically into nutrient molecules ( digests it ), and absorbs the nutrients into the bloodstream, then, it rids the body of indigestible remains ( defecates )  Activities Occurring in the Mouth, Pharynx, and Esophagus o Activities that occur in the mouth , pharynx , and esophagus are food ingestion , food breakdown , and food propulsionFood Ingestion and Breakdown o Once food is placed in the mouth , both mechanical and chemical digestion begin  Physical breakdown:1 st^ step  Food is physically broken down into smaller particles by chewingChemical breakdown:2 nd^ step  Food is mixed with saliva , salivary amylase begins the chemical digestion of starch, breaking it down into maltoseStimulation of saliva:  Simple pressure of anything put into the mouth and chewed will also stimulate the release of salivaPassageways:Pharynx and the esophagus have no digestive function  Simply provide passageways to carry food to the next processing site, the stomach  Food Propulsion – Swallowing and Peristalsis o Food to be sent on its way to the mouth , it must first be swallowedDeglutition:  Or swallowing  Complex process that involves the coordinated activity of several structures: o Tongue , soft palate , pharynx , and esophagusBuccal phase of deglutition:1 st^ phaseVoluntary buccal phase – occurs in the mouth o Once the food has been chewed and well mixed saliva  Bolus ( food mass ) o Forced into the pharynx by the tongue